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Longitudinal studies also show positive effects on sexual function and mood 16 Large-scale prospective studies are lacking. As a result, inducers of CYP3A4 and other cytochrome P enzymes, such as carbamazepinephenobarbitalphenytoinrifampinrifampicinand St. Spironolactone is one of the most common medications used to suppress endogenous testosterone in trans female patients. Just 2 years later, Winfrey would feature another interview that elicited many of the same audience reactions.

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Journal of Pediatric and Adolescent Gynecology.

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